Vazoplex Study Results

Total patients = 50 females, ages 28 – 64 years old

Group Population

Group I: Females complaining of vaginal dryness and dyspareunia

A. With dyspareunia (Group A) – 10 patients ages 45 – 62
B. Without dyspareunia (Group B) – 2 patients ages 45 & 48

Group II: Loss of libido

A. Frequent (Group A) – 17 patients ages 34 - 52
B. Occasional (Group B) – 13 patients ages 28 - 53

Group III: No loss of libido – 8 patients ages 28 – 37


Group Results

Group I:

Dryness completely resolved in 9 of 10 Group A & 2 of 2 in Group B

Improved libido in 8 of 10 Group A/ 2 of 2 in Group B

Dyspareunia resolved in ALL Group A patients

Sexual performance enhanced significantly in entire patient population

Side Effects:

- 1 patient in Group A with transient burning sensation (of less than 1 minute)

- 1 patient with topical irritation which was resolved with small amt of Hydrocortisone cream in less than 24 hrs. Did not reoccur after later usage of Vazoplex. Patient had history of "sensitive skin."

Group II:

Libido improved in 26 of 30

- 14 of 17 in Group A

- 12 of 13 in Group B

Sexual performance enhanced significantly in entire patient population

Side Effects:

- 3 patients with transient burning sensation (of less than 1 minute)

Group III:

Libido enhanced in all patients

No side effects

Details:

All patients were seen at 21 days and at 60 days and were given samples at each interval. Approximately half of the entire group (mostly less than 40 years old) requested "refills" prior to their scheduled visit. Even those patients that had the initial side effects wanted refills. Side effects seemed to correlate to the amount used.

Conclusions:

1. Vaginal dryness improved in over 90% of the patients.

2. Dyspareunia improved in 100% of the patients.

3. Libido improved in almost 90% of the patients.

4. Sexual performance was enhanced in 100% of the patient population.

5. Side effects were minimal, occurring in < 10% of the patients. Those that were experienced were considered mild and transient.

6. Only one patient experienced topical irritation that responded to Hydrocortisone cream in less than 24 hours. The irritation did not reoccur with further usage. My impression is that the patient misapplied the Vazoplex to epidermal tissue not in the vaginal introitus, but more in the symphisis pubis area. I do not consider this significant and questioned other patients, none of whom had any topical irritation.

7. Vazoplex is an effective product for vaginal dryness, dyspareunia, enhancing sexual performance and improving libido (even in patients that did not realize they had a diminished libido).

 





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